Brain Health: What Are The Benefits of Taking Vitamin B1 (Thiamine)?

I’m David Tomen author of nootropics expert calm and in this video I’m going to share with you what I know about vitamin b1 or thiamine as a nootropic what it is why we use it the science behind it dosage and side effects vitamin b1 or thiamine is the first of the B complex vitamins identified and designated as b1 as a result Japanese researchers were the first to determine that something was missing in the diet of those who paid only polished rice polished rice is one of the first processed foods and of course there were problems right from the start the brand coating on rice kernels contain what was later identified as thiamine or what we now know was biting b1 the Japanese population were severely thiamine deficient on this rice only diet large numbers of the population were suffering from beriberi a central nervous system disorder caused by lack of thiamine when scientists determined it was thiamine that was behind it this major countrywide health crisis they went on to develop cell beauty mean it was better absorbed by the brain than standard thiamine now your body does not produce thiamine on its own so you must get it from food including beef brewers yeast legumes like beans and lentils milk nuts oats oranges pork rice seeds wheat whole grain cereals and yeast but thiamine has poor bioavailability when taken as a nootropic supplement a derivative with diamond called saw beauty amine is fat soluble compound that is easily digested and readily crosses the blood-brain barrier sell beauty Amin is a synthetic version of vitamin b1 it is to be one molecules chemically bonded together thiamine is water-soluble and does not easily cross the blood-brain barrier cell ability mean is fat soluble compound that easily crosses this barrier Subutai mean functions in the body just like thiamine but because it’s more bioavailable it’s more effective than thiamine well first diamond increases levels of thiamine pyrophosphate or TPP TPP is directly involved in the citric acid or Krebs cycle in the brain this cycle breaks fatty acids amino acids in monosaccharides into smaller molecules that produce and dentin adenosine triphosphate or ATP energy for you mitochondria and provide the building blocks of the molecules needed to produce brain cells a deficiency of TPP can eventually show up as Wernicke encephalopathy or Korsakoff syndrome now in our society this syndrome is typically caused by chronic alcoholism but it can also occur after obesity or bariatric surgery Crohn’s disease and our exia diabetes and if you’re on kidney dialysis symptoms of wernicke Korsakov syndrome include confusion inability to form memories loss of memories and muscle coordination confabulation which is making up stories and vision changes and can ultimately and very rapidly lead to coma and death now less severe cases of thiamine deficiency include fatigue weight loss irritability and confusion in the second way thiamine also contributes to the production of the enzyme P D H which is essential for making the neurotransmitter acetylcholine and for the synthesis of myelin which forms that the sheath around the axons of neurons ensuring that these neurons can conduct electrical signals the citric acid cycle or the Krebs cycle an enzyme a kg d h play a role in maintaining optimal levels of the neurotransmitters glutamate and GABA and when thiamine levels decrease the activity of these enzymes are reduced diamond occurs in your body is free thiamine and various phosphorylated forms including thiamine mono phosphate or TMP thiamine triphosphate or TTP and thiamine pyrophosphate TP TPP which is also known as thiamine diphosphate the synthesis of TPP from free thiamine requires magnesium adenosine triphosphate or ATP and the enzyme thiamine pyrophosphate Tenet’s TPP is required for the metabolism of carbohydrates and branched chain amino acids thiamine is directly involved in the citric acid cycle or the krebs cycle that provides adenosine triphosphate energy for mitochondria thiamine also plays a role in maintaining optimal levels of the neurotransmitters glutamate and GABA and contributing to the production of the enzyme P D H which is essential for making the neurotransmitter acetylcholine thiamine will boost cognition memory and decision-making and provides very effective as the oolitic or antidepressant qualities Simon is water-soluble and has been shown to improve glutamate and GABA neurological transmissions if you are perfectly healthy and you don’t have a thiamine deficiency it’s not likely that you’ll feel anything after supplementing with thiamine but I’ve come across study after study and reports on forums where lab tests showed firemen and thiamine triphosphate within range and yet people were dealing with mild fireman deficiency the problem is mild thiamine deficiency can turn your world upside down if you are hypothyroid or dearly dealing with Hashimoto’s there is a very good chance that you would benefit from thiamine supplementation the same with diabetes fibromyalgia and inflammatory bowel disease neuro hackers report that supplementing with thiamine is an effective mosquito repellent and I find that personally it helps when everybody else is getting bitten by mosquitoes I’m using cell beauty mean every day and I do not get bit by mosquitoes now many report the thymus supplementation boosts attention energy and motivation a reduction in brain fog and increased mental clarity with less anxiety those dealing with fibromyalgia and nerve pain report a significant decrease in pain levels now most of the research conducted on vitamin b1 has been done with people dealing with fatigue or pain associated with fibromyalgia thyroid disease and other debilitating conditions and most have very few participants but the results in every trial that I found are profound if you want to see details of these studies go to nootropics expert comment search for thiamine or click on the link below this video I’ve got one on how fireman improves the symptoms of fibromyalgia I’ve got another study on thiamine for chronic fatigue syndrome and I’ve got another study for thiamine and Hashimoto’s so to see these studies go to nootropics expert comment search for thiamine the recommended dosage of vitamin b1 or thiamine according to the American FDA is 1.2 milligrams a day pregnant and breastfeeding women is a whopping 4 milligrams per day now many neuro hackers would laugh at these recommendations mild thiamine deficiency affects a significant segment of the population in any country well those clinical studies on thiamine doses using thiamine doses range from 300 all the way up to 1,800 milligrams a day the bottom line is that diamond dosing is completely up to you when the side effects and there’s very little side effects or no side effects reported even at high doses now the Mayo Clinic recommends for menstrual cramps 100 milligrams a day epilepsy 50 milligrams alcoholic liver disease and withdrawal a hundred milligrams of the injection by injection of thiamine hydrochloride for coma or hypothermia a hundred milligram injections thiamine deficiency due to nutrition 100 milligram injections and for Warnecke Korsakoff syndrome five to 200 milligram injections some natural health clinics offer very expensive thiamine therapy intravenously and doses are usually 25 to 50 milligrams a session Simon is non-toxic so is considered well tolerated and say side effects are rare and very high doses can include upset stomach if you are taking digoxin diuretics or de lanten you should consult with your doctor before supplementing with thiamine címon hydrochloride or HCI is most vitamin b1 or thiamine supplements available from online retailers and vitamin shops come as thiamine hydrochloride and come in 50 to 500 milligram tablets or capsules benfotiamine is a synthetic s acyl derivative of thiamine and it’s a fat soluble form of thiamine that is much more bioavailable than HCI benfotiamine typically comes in 150 to 250 milligrams capsules dosage is up to 900 milligrams a day and then there’s tetra hydro furfural sulfide or TTFN d also known as first salt evening tea tea FD is a disulfide derivative of thiamine developed in Japan for treating beriberi it’s a synthetic form of thiamine that naturally occurs in garlic TTFN tea is a form of thiamine that is water-soluble and much more difficult to find in vitamin shops brand names include names like Lippo thiamine Advent in ban lipoid and jeu de lor TT FD comes in 50 milligram capsules and the primary side effect of using it is that you smell like garlic after taking it and then we have my preferred form cell beauty mean saw Beauty mean is sold for godard of enhancement it’s in a tablet capsule and powder form I buy it in powder form and I make my own capsules tablets and capsules ready main are usually 750 milligrams each so beauty mean is a synthetic version of thiamine it’s just two thousand molecules bound together it’s sold as a prescription medication in some countries under brand names like our Kalyan Bice Beauty thiamine and a couple of other names so my nootropics expert recommendation for vitamin b1 or thiamine is 50 to 100 milligrams per day and that’s my report on vitamin b1 if you want to see links to the studies I talked about go tree nootropics expert comment search for vitamin b1 or thiamine or click on the link below this video there you’ll find a full transcript of this video and you’ll find dozens of articles and all the well-known nootropics on the tropics expert and if you have any questions or you want to share your experience using either thiamine or cell beauty you mean please use the comment section at the bottom of the post on nootropics expert I respond to comments and questions at nootropics expert usually the same day and if you want to see more videos and all the best in tropics use today subscribe to this channel before you leave I’ll be putting up new videos on new tropics and optimizing your brain every week I’m David Tomen author and nootropics expert